 |
2nd
and 3rd degree burns. |
 |
Donor sites
and grafting areas. |
 |
Surface bacterial infections
- invloving wounds - cutaneos ulcers or various
pyodermas. |
 |
Minor burns |
 |
Staphylococcus
aureus. |
 |
Streptococcus. |
 |
Escherichia coli. |
 |
Colestridium perfringens. |
 |
Aerobacter aerogenes. |
 |
Proteus. |
 |
Topifuran Ointment
0.2% Nitrofurazone, which is an FDA approved
material since 1945 till now. |
 |
It is time tested
as most effective bactericidal agent against
most Gm +ve and Gm -ve bacteria commonly causing
surface infection. |
 |
Nitrofurazone shows minimal
side effects specially when applied topically
in non absorbable base. |
 |
Topifuran prepared
in macrogols base which is water soluble,
non absorbable and less toxic. (Carbo wax
base). |
 |
Macrogols base
has high molecular weight and shows higher
viscosity. |
 |
Macrogols generally appear
to have low toxicity specially with the higher
molecular weight. |