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The most effective bactericidal agent for most pathogens commonly causing surface iinfections. Even when theree is a real or potential problem of bacterial resistance.

High Efficacy:
2nd and 3rd degree burns.
Donor sites and grafting areas.
Surface bacterial infections - invloving wounds - cutaneos ulcers or various pyodermas.
Minor burns

Including:
Staphylococcus aureus.
Streptococcus.
Escherichia coli.
Colestridium perfringens.
Aerobacter aerogenes.
Proteus.

Wide Safety Profile:
1) Concerning the active principle:
Topifuran Ointment 0.2% Nitrofurazone, which is an FDA approved material since 1945 till now.
It is time tested as most effective bactericidal agent against most Gm +ve and Gm -ve bacteria commonly causing surface infection.
Nitrofurazone shows minimal side effects specially when applied topically in non absorbable base.

2) Concerning the base:
Topifuran prepared in macrogols base which is water soluble, non absorbable and less toxic. (Carbo wax base).
Macrogols base has high molecular weight and shows higher viscosity.
Macrogols generally appear to have low toxicity specially with the higher molecular weight.

Dosage and Administration:
Apply directly to lesion or place on a gauze.
To be applied daily or every few days.

 
 
 
 
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