Management of poison ingestion along with activated
charcoal.
As a sweetening agent for diabetic patients.
Contraindications:
Liver failure.
Renal failure.
Hereditary fructose intolerance.
Adverse Reactions:
None reported at the stated dosage.
Overdose:
May cause flatulence, abdominal distention and diarrhea.
Pharmacokinetics:
Absorption:
Poor from the GIT.
Distribution:
None.
Metabolism:
The small amount of sorbitol absorbed from the GIT
is converted in the liver to fructose . The end metabolite
is CO2.
Excretion:
* Mainly in feces.
* About 3% in urine.
Dosage and Administration:
1- Constipation:
Orally:
Dissolve the contents of 2-3 packets in 1/2 glass
of water, drink at bedtime.
Rectally:
Dissolve the contents of 5-10 packets in 200 ml
of water to be used as an enema before bedtime.
2- Gallbladder insufficiency:
Dissolve the contents of one packet in 1/2 glass
of water and take orally 10 minutes before meals
1-3 times daily.
3- Poisoning:
Dissolve Sorbit (1g/kg) in 250ml of water, mix
with activated charcoal (1g/kg) and give orally
or by gastric tube. Repeat one-half the dose if
there is no charcoal stool after 4-6 hours.
4- As a sweetening agent:
As recommended by the physician.
How Supplied:
Boxes containing 20 packets,
Each packet contains 5 g. Sorbitol powder.
